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Rockefeller University Research Specialist in New York, New York

Job: IRC23726

Description

Job Title Research Specialist

Laboratory / Department Mammalian Cell Biology and Development

Department Description

Our laboratory begins with molecular mechanisms, and we work our way to the genetic bases of human diseases that are caused by defects in the proteins we study. We have repeatedly used this reverse genetic approach to successfully elucidate the genetic bases of a variety of human and mouse disorders, ranging from blistering skin disorders and skin tumors/cancers, to a rare form of muscle degeneration and a sensory neurological disorder.

Detailed Description

The Research Specialist will work as a part of a highly talented team of molecular, cell, and developmental biologists seeking an understanding of the properties of adult skin stem cells and how aberrations in their biology can lead to skin disorders, including cancers. The Research Specialist will be responsible for designing novel DNA constructs for genetic engineering in primary stem cells or in mice, designing and optimizing of reporter constructs and primers for genotyping, performing CRISPR/Cas9 cloning, and testing mouse founder lines for proper gene expression. Depending on a candidates' science and experience, will have the opportunity to be involved in related research projects.

Job Requirements

Master's degree and a minimum of 5 years of experience in designing DNA constructs and CRISPR/Cas9 cloning. Experience with tissue culture a plus. Must be a fast and independent learner, thrive in a fast-paced research lab, and interact well with a dynamic group of postdoctoral researchers and students.

Additional Details

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans

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