Rockefeller University Research Assistant in New York, New York
Job Title Research Assistant
Laboratory / Department Molecular and Cellular Neuroscience
The Laboratory of Molecular and Cellular Neuroscience studies the molecular defects responsible for neurological and psychiatric disorders including Alzheimer's disease, major depressive disorder, Parkinson's disease, and obsessive compulsive disorder, as well as the molecular mechanisms by which neuro- and psychoactive drugs produce their pharmacological actions in these disorders. Research from the laboratory has demonstrated that most neurotransmitters and neuromodulators achieve their actions and interactions on post-synaptic neurons through a process called "slow synaptic transmission." This process involves activation of highly complex signal transduction cascades. For the last 10 years, the group has applied this knowledge and developed a state-of-the-art methodologies (eg. BacTRAP), to the study of the molecular pathways behind various neurological and psychiatric disorders.
Under the supervision of the principal investigator and research team, the Research Assistant will assist in a project aiming to identify cellular pathways that are involved in Alzheimer's disease using a variety of cellular and animal models. Will culture cells, generate mouse models of Alzheimer's disease, and conduct work using cell lines, iPS cells, molecular biology techniques, and biochemical analyses.
Bachelor's degree in science required; educational emphasis in genetics, neuroscience, molecular biology, or biochemistry preferred. Must have an understanding of common genetic and biochemical principles, as well as proficiency in standard molecular and cell biology procedures. Experience with primary cell culture preparation, flow cytometry, and immunohistochemical methods preferred. Must have excellent problem solving and communications skills, the ability to work independently as well as part of a team, and be able to exercise independent judgment.
Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled