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Rockefeller University Research Assistant, Neurogenetics and Behavior in New York, New York

Job: IRC24845


Job Title Research Assistant, Neurogenetics and Behavior

Laboratory / Department Neurogenetics and Behavior

Department Description

The Vosshall Lab seeks to understand how an animal's behavior is guided by integrating sensory input with information about its internal physiological state. The group studies this problem in the Aedes aegypti mosquito, a vector for Zika, Dengue, Chikungunya, and Yellow Fever. For a female mosquito to complete egg development, the insect requires a blood meal. Acquiring that blood from a human is an innate behavior that potentially spreads dangerous infectious diseases carried by the insect. The Lab has developed CRISPR/Cas9 genome-editing tools , which allows the team to apply a genetic approach to understanding how female mosquitoes integrate sensory cues such as body odor, heat, and exhaled carbon dioxide to hunt their human hosts. The group is currently pursuing a number of questions: Why are some people more attractive to mosquitoes than others? How do insect repellents work? How are multiple sensory cues integrated in the mosquito brain to elicit innate behaviors? How do female mosquitoes select a body of water suitable for egg laying? This work provides insights into potential methods to control mosquitoes' biting behavior.

Detailed Description

The Research Assistant will work on several projects performing behavioral assays with female Aedes aegypti mosquito strains to study how attracted they are to human skin odor. One project will investigate why some people are more attractive to mosquitoes than others. A second project will involve testing new compounds that may reduce mosquito biting behavior, with the eventual goal of developing these compounds into new methods of mosquito control. Responsibilities include managing the rearing of transgenic and CRISPR-Cas9 knock-out mosquito strains, sorting for fluorescent animals, genotyping, strain maintenance, and interfacing with students and postdocs on specific projects. The Research Assistant will join a vibrant, welcoming, and diverse workplace and will have the opportunity to seek mentorship from senior researchers to meet ongoing educational and professional goals.

Job Requirements

Bachelor's Degree in science required; educational emphasis in the biological sciences preferred. Must have exceptional organizational skills and the ability to be focused, careful, and meticulous. Must be comfortable multi-tasking and reporting to multiple members of the laboratory. Experience in molecular biology, genotyping, and fluorescence microscopy preferred. Will be trained in mosquito handling, performing behavioral assays, and data analysis.

Additional Details

The Rockefeller University is an Equal Opportunity Employer - Minorities/Women/Disabled/Veterans